28-April-2017: MCIN demonstrates the Big Brain to future scientists

On April 28th, students from Gerald McShane Elementary school and Rosemount High School experienced the Big Brain on a recent tour of the Neuro.  The students were given an overview of the history and role of brain atlases in modern medicine, the creation of the Big Brain dataset, and its current use in both research and clinical applications.

12-April-2017: Dr R. Buxton visits the MCIN

Dr. Richard Buxton, Professor of Radiology at UC San Diego, visited the MCIN recently after delivering his talk  “Potential of Quanta FMI” at the Neuro. During his visit, Dr. Buxton experienced the Big Brain with Dr. Evans.

8-Mar-2017: New paper published by Dr. Y. Iturria-Medina and colleagues

A recent paper entitled “Multifactorial causal model of brain (dis)organization and therapeutic intervention: Application to Alzheimer’s disease” by Dr. Yasser Iturria-Medina and colleagues of the MCIN was published in Science Direct.

1-s2.0-S1053811917301684-fx1In this article, we focus on describing the model and applying it at the population-based level for studying late onset Alzheimer’s disease (LOAD). By interrelating six different neuroimaging modalities and cognitive measurements, this model accurately predicts spatiotemporal alterations in brain amyloid-β (Aβ) burden, glucose metabolism, vascular flow, resting state functional activity, structural properties, and cognitive integrity. The results suggest that a vascular dysregulation may be the most-likely initial pathologic event leading to LOAD.

Highlights include:

  • A multifactorial causal model (MCM) of brain (dis)organization and therapeutic intervention is proposed.
  • Prediction of complex multifactorial alterations in Alzheimer’s disease, using six different neuroimaging modalities and the MCM.
  • Identification of potential triggering pathological events and associated “epicenter” brain regions.
  • Identification and characterization of direct multifactorial interactions, vulnerability, and influence level of each biological factor.
  • Identification of optimum therapeutic strategies to stop/reverse disease.

Read the full paper HERE

17-Jan-2017: the MCIN makes Discovery’s top stories of 2016


The research done at the MCIN was mentioned as the 12th top story of 2016.

The story entitled “Big Data May Lead to Earlier Alzheimer’s Diagnosis: A new algorithm charts a 30-year trajectory for biological risk factors” by Linda Marsa describes the technique developed at the MCIN that may detect Alzheimers in its earliest stages.

The full article can be seen here.

16-Dec-2016: $20M donated to create Tanenbaum Open Science Institute


The Montreal Neurological Institute is hoping to change the way discoveries are made with the help of a multi-million dollar donation.

Larry Tanenbaum and his wife Judy are giving $20 million to create the Tanenbaum Open Science Institute, which will collect and make available research on neurological diseases.

The official announcement was made Friday in conjunction with McGill University, which is affiliated with the institute, and Prime Minister Justin Trudeau.

Modeled after the idea of open source software, the institute will also keep the research patent-free and make its findings freely accessible worldwide.

The approach is meant to speed up the time it takes for research to translate into treatment for patients.

“Our goal is simple: to accelerate brain research and discovery to relieve suffering,” said Tanenbaum.

– Caption from Read the full article here

‟Today, we take an important step forward in opening up new horizons in neuroscience research and discovery,” said Mr. Larry Tanenbaum. ‟Our digital world provides for unprecedented opportunities to leverage advances in technology to the benefit of science.  That is what we are celebrating here today: the transformation of research, the removal of barriers, the breaking of silos and, most of all, the courage of researchers to put patients and progress ahead of all other considerations.”

– Caption from McGill Newsroom. Read the full article here

13-Dec-2016: Ludmer Centre Neuroscience Guest Lectures – Day 2


December 13th marked the second day of the Ludmer Centre Guest Lectures held at the MNI.

Highlights from todays event included presentations on the topics of:

  • Epigenetics & Mental Health
  • Genomics, Bioinformatics & Statistical Genetics
  • Neuroimaging / Neuroinformatics
12-Dec-2016: Ludmer Centre Neuroscience Guest Lectures

December 12th marked the first of two days of talks hosted by the Ludmer Centre.

Highlights from the opening of the event held at the MNI included:

  • A Presentation from Yale University Professor of Psychiatry & Psychology David Glahn, PhD, entitled Localizing Genetic Loci for Affective and Psychotic Disorders with Endophenotypes Mechanisms and Molecules.
  • A Presentation from David Kennedy, PhD, from the Department of Psychiatry of the University of Massachusetts Medical Center entitled Advancing Reproducibility in Neuroimaging Computation the ReproNim Concepts.
29-Nov-2016: Dr Low presents “Harnessing the Brain’s Whispers” at the MNI

Screen Shot 2016-11-29 at 10.36.03 AM

On Nov 29th, Dr. Low, CEO of NeuroVigil spoke to the MNI on about various topics including the SPEARS algorithm for measuring sleep patterns, and the iBrain device allows researchers to conduct studies with minimal setup and provides patients with a less-intrusive experience. Additionally, Dr. Low spoke about an initiative to build a Canadian NeuroZone.

Link to NeuroVigil website here


17-Nov-2016: Innovation week at the MNI


Members of the MCIN assisted in organizing, and participating in Innovation week, a collaboration of minds from a variety of career backgrounds and studies. The event focused on how people with different backgrounds, skill,s and education come together in todays neuroscience research.


15-Nov-2016: Principal of McGill Dr. Suzanne Fortier and the Principal’s International Advisory Board visit the MCIN

fortier_4The Principal of McGill, Dr. Suzanne Fortier and the Principal’s International Advisory Board visited MCIN on Tuesday November 15. Presentations by Drs. Edward Fon, Michael Meaney and Penelope Kostopoulos described the open science initiatives at the MNI and the role of the Ludmer Centre and MCIN more specifically in the Healthy Brain Healthy Lifes project and other international neuroscience initiatives.