Neurodegeneration

We research neurodegenerative diseases by exploring various neuroimaging, metabolic, behavioral and genetic data from large cohort studies of normal aging and neurodegenerative diseases.  

Our research is primarily focused on:

Hypothetical (A, Jack et al) versus Data-driven (B, Itturia-Medina et al.) models of LOAD progression.

 

Diagnostic Biomarkers

Developing reliable and sensitive neuroimaging biomarkers that help clinicians to observe the dynamics of disease progression in population data, or to detect the onset of neurodegenerative disease before it becomes symptomatic. 

Read our publications here

 

Reconstruction of individual Aß propagation/deposition histories using an ESM

Modeling Disease Progression

Investigating the correlations between environmental, behavioural or physiological risk factors that determine the severity or onset of the disease.  

Read our publications here

Visualization

Our sophisticated cyber-infrastructure supports normative models, analytical pipelines and data integration platforms, that enable us to perform multivariate statistical analysis, and mathematical modeling on thousands of longitudinally collected datasets.

 

Links to Neurodegeneration related research and initiatives from the MCIN


Canadian Consortium on Neurodegeneration in Aging (CCNA)

Canadian Consortium on Neurodegeneration in Aging (CCNA)

We are actively supporting the Canadian Consortium on Neurodegeneration in Aging (CCNA), which will be the premier research hub for all aspects of research involving neurodegenerative diseases that affect cognition in aging – including Alzheimer’s disease. The CCNA is supported by CIHR and many partners and is the Canadian component of the CIHR Dementia Research Strategy.


Montreal Alzheimer Research for a Cure

Montreal Alzheimer Research for a Cure

The Montreal Alzheimer Research for a Cure is collaboration between the Reitman Family Foundation, the Jewish General Hospital, and the Neuro, with the goal of finding a cure for Alzheimer through the funding of scientific research. With your help, we can find a cure.